Description
Diacerein+Glucosamine Sulfate & Potassium Chloride is indicated in osteoarthritis. The ingredients of this combination act synergistically in providing relief, minimizing inflammation, and maintaining joint health.
Mechanism of Action of Diacerein +Glucosamine Sulphate +Potassium Tablets
Diacerein +Glucosamine Sulphate +Potassium Tablets is a therapeutic mixture administered in the management of osteoarthritis.
Diacerein is an anti-inflammatory agent. It inhibits interleukin-1β, a protein that promotes inflammation and cartilage degradation in the joints. By inhibiting this protein, Diacerein prevents inflammation and slows cartilage degradation.
Glucosamine Sulfate + Potassium supplies the building blocks necessary to synthesize glycosaminoglycan, an important structural element of cartilage. It facilitates the repair of damaged cartilage, decreases inflammation, and enhances lubrication and shock absorption in the joints.
Uses of Diacerein +Glucosamine Sulphate +Potassium Tablets
The main application of Diacerein Glucosamine Sulphate Potassium Tablets is in the treatment of osteoarthritis. This combination drug falls under the category of anti-inflammatory and cartilage-forming drugs.
Secondary applications of this drug include assisting in reducing joint pain, stiffness, and inflammation. Additionally, it helps to retard the development of osteoarthritis and lower cartilage loss. It helps to enhance joint mobility and function in patients suffering from knee and hip osteoarthritis.
Expert Advice
Dosage Forms Available
- Diacerein + Glucosamine Sulfate Potassium Chloride comes in oral tablets and capsules.
- The medication is administered orally.
Age and Dose Restrictions
This drug is used in adults and children over the age of 18 years.
Contraindications
- Diacerein +Glucosamine Sulphate +Potassium Tablets should not be given to patients with advanced liver or kidney damage.
- It must not be taken by a person with inflammatory bowel disease such as Crohn’s disease or ulcerative colitis.
- It must be avoided by patients suffering from Glucose-6-phosphate dehydrogenase (G6PD) deficiency.
- Individuals who have hemochromatosis must avoid taking this medication as well.
Other Medications to Avoid
Diacerein +Glucosamine Sulphate +Potassium Tablets can interact with blood thinners (warfarin, aspirin), diabetes tablets (metformin and insulin), antibiotics (norfloxacin, pefloxacin), and cancer chemotherapy agents (methotrexate).
Overdose and Missed Dose
- An overdose of Diacerein + Glucosamine Sulphate + Potassium Tablets can cause serious nausea, vomiting, diarrhoea, or skin rashes. If it happens, talk to your doctor right away.
- If you forget a dose, take one as soon as possible. If your next dose is due, skip the forgotten dose and go back to your normal schedule. Never take a double dose to replace a missed dose.
Management of Side Effects
- Most of the side effects are transient and are usually not harmful and subside on stopping this medicine. If you do get any serious side effects or worsening of any of the symptoms, please inform your doctor.
- Have plenty of fluids to help control side effects such as diarrhoea.
- Taking the medication with food can decrease gastrointestinal side effects.
- Notify your doctor right away if you have severe stomach pain, yellowing of the skin, easy bruising or bleeding.
Use in Driving and Operating Machinery
This drug can cause drowsiness or dizziness in some patients. If such symptoms occur, it is recommended not to drive or work with heavy machinery.
Use in Pregnancy and Lactation
It is best to consult a physician before the use of this drug in pregnancy or during breastfeeding since its safety in these contexts is not fully established.
Caution in Other Conditions
- Diacerein +Glucosamine Sulphate +Potassium Tablets must be used with care in patients suffering from liver or kidney disease.
- It must be used carefully in patients having a bleeding disorder or diabetes.
Special Dietary and Lifestyle Recommendations
- Adequate physical exercise helps in controlling osteoarthritis. It makes the muscles of the joints stronger and increases flexibility.
- Make an effort to stay at a healthy weight because being overweight causes added stress on weight-bearing joints such as hips and knees, leading to worsened symptoms of osteoarthritis.
- Eat a balanced diet full of fruits, vegetables, lean protein and omega-3 fatty acids, which can decrease inflammation and enhance overall health.
